Sarah Gitto

Sarah Gitto

Company: University of Pennsylvania

Job title: Project Lead

Seminars:

Autologous Tumor/TIL Avatar Development to Study Patient-Specific Response to Immunotherapy 9:45 am

• Patient-matched orthotopic PDX/ TIL models were developed and validated. • TILs with autologous tumor reactivity were successfully expanded from donor HGSOC for infusion. • TILs co-cultured with autologous tumor cells exhibited HLA-dependent IFNγ production and activation. • TILs in combination with anti-PD-1 significantly increased patient-matched tumor cell lysis and increased overall survivalRead more

day: Day Two

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