Virna Cortez-Retamozo
Company: Sanofi
Job title: Senior Principal Scientist
Seminars:
Industry-Focused Panel Discussion 5:00 pm
During development of new immuno-modulatory therapeutics, when is the best time to evaluate cytokine release? Options include: As a stand-alone assay comparing molecules in a side-by-side assay for lead selection During analysis of preclinical efficacy as part of the overall mode of action Later stage, post preclinical efficacy to determine safety/tox prior to IND filing.Read more
day: Day One
Discussion/Q&A 2:25 pm
day: Day One
Improved Antitumor Activity of Local immunotherapy with mRNA Encoding Cytokines and Immune Checkpoint Blockade in Multiple Preclinical Syngeneic Tumor models with “Cold” and “Hot” Immune Phenotype 1:50 pm
Anti-tumor activity of intratumoral cytokine mRNA therapy in combination with immune check blockade in 12 syngeneic mouse models with “cold” and “hot” immune phenotypes Immune mediated mechanism of action of combination therapy with cytokine mRNA and anti-PD-1 antibodyRead more
day: Day One