Basile Siewe

Basile Siewe

Company: The Jackson Laboratory

Job title: Director - Business Development

Seminars:

Discussion/Q&A 10:20 am

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day: Day One

Patient-Derived Tumor Xenografts in Humanized NSG-SGM3 Mice: A New Immuno-Oncology Platform 9:00 am

The addition of 3 human cytokines (GM-CSF, IL-3 & Kit Ligand) into the NSG mouse provides for a more robust myeloid compartment  after humanization Showcase data on the myeloid engraftment kinetics and also show checkpoint inhibitor efficacy against several PDX Leverage humanized mice to assess the risk of immunotherapeutic-associated cytokine release syndrome CRS)Read more

day: Day One

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