Erin Riegler

Erin Riegler

Company: Chimera Bioengineeing

Job title: Scientist


IL12-Armored CAR-T: Multi-Dimensional Data Analysis to Assess both Efficacy & Safety Considerations in an NSG Mouse Model 11:00 am

• 4th generation “Armored” CAR-T cells express a biologic payload to assist in overcoming hostile tumor microenvironments • Many payloads, such as IL12, have potentially toxic effects when dosed systemically • Chimera’s proprietary GOLD CAR-T cells restrict the payload delivery to the local tumor microenvironment • We used measurements of IL12 levels and other pro-inflammatory…Read more

day: Day Two

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