Influence of the Gut Microbiome Toward Preclinical Translation of Cancer Immunotherapy

Time: 1:15 pm
day: Day One


• Key species of bacteria exist that influence preclinical efficacy in tumor models
• Pre-treatment regimens, such as antibiotics, need to be considered in most preclinical models as these can impact the endogenous microbiome and may impact clinical efficacy
• Not all microbiomes are created equal and the depth at which we sequence (16S, metagenomic, etc) is critical to align on to speak the same language across microbiome studies for biomarkers and possible treatment modalities